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Cally Roper Selected Research

Pyrimethamine (Daraprim)

1/2017Unexpected selections of Plasmodium falciparum polymorphisms in previously treatment-naïve areas after monthly presumptive administration of three different anti-malarial drugs in Liberia 1976-78.
7/2010Drug coverage in treatment of malaria and the consequences for resistance evolution--evidence from the use of sulphadoxine/pyrimethamine.
6/2008Increased gametocytemia after treatment: an early parasitological indicator of emerging sulfadoxine-pyrimethamine resistance in falciparum malaria.
9/2005Reduced variation around drug-resistant dhfr alleles in African Plasmodium falciparum.
8/2004Intercontinental spread of pyrimethamine-resistant malaria.
4/2003Molecular determination of point mutation haplotypes in the dihydrofolate reductase and dihydropteroate synthase of Plasmodium falciparum in three districts of northern Tanzania.

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Cally Roper Research Topics

Disease

43Malaria
01/2021 - 04/2003
9Falciparum Malaria (Plasmodium falciparum Malaria)
01/2017 - 05/2007
6Infections
01/2020 - 06/2008
2Birth Weight (Birth Weights)
01/2019 - 02/2013
2Reinfection
03/2015 - 02/2007
1Coinfection
01/2020
1Pregnancy Complications
10/2018
1Imported Communicable Diseases
12/2016
1Vivax Malaria
11/2015
1Asymptomatic Infections
01/2011

Drug/Important Bio-Agent (IBA)

21pyrimethamine drug combination fanasil (Fansidar)FDA Link
12/2019 - 04/2003
12Antimalarials (Antimalarial Agents)IBA
09/2019 - 04/2003
10artemisinin (artemisinine)IBA
01/2021 - 05/2007
8Pharmaceutical PreparationsIBA
09/2019 - 02/2007
6Chloroquine (Aralen)FDA LinkGeneric
01/2017 - 04/2003
6Pyrimethamine (Daraprim)FDA Link
01/2017 - 04/2003
4DNA (Deoxyribonucleic Acid)IBA
01/2020 - 07/2012
4Amodiaquine (Camoquin)FDA Link
01/2018 - 05/2007
3Lumefantrine Drug Combination Artemether (Coartem)FDA Link
01/2018 - 02/2008
3Sulfadoxine (Sulformethoxine)FDA Link
06/2008 - 04/2003
2VaccinesIBA
10/2018 - 06/2014
2ArtesunateIBA
01/2018 - 03/2015
2Dihydropteroate Synthase (Dihydropteroate Synthetase)IBA
12/2016 - 12/2015
2Codon (Codons)IBA
12/2016 - 12/2015
2Folic Acid AntagonistsIBA
10/2013 - 06/2008
1succinylated wheat germ agglutininIBA
01/2020
1chlorproguanilIBA
01/2017
1Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)IBA
12/2016
1PrimaquineFDA Link
11/2015
1Genetic Markers (Genetic Marker)IBA
06/2014
1Indicators and Reagents (Reagents)IBA
06/2008
1InsecticidesIBA
02/2007

Therapy/Procedure

11Therapeutics
01/2019 - 05/2007
3Aftercare (After-Treatment)
03/2015 - 02/2007
2Chemoprevention
12/2019 - 12/2016
1Prenatal Care (Care, Prenatal)
12/2019
1Mosquito Nets
06/2015